Report of the Task Group on Reference Manis, admittedly, a bit much for most readers. And then they went and did it anyway. It is available for download in its entire 500 page glory, in case you ever need to refer to it for something as granular as the fluid content of a newbortn's thymus, or the normal boron concentration of human hair (0.2-0.8 mg/100 g, by the way). The indicator dilution principle is based on. Of man which are known to be important or which are likely to be significant for estimation of dose from sources of radiation within or outside the body", because "however important or desirable it may be to have a Reference Man embodying all known characteristics of man, the task of defining such a Reference Man is clearly beyond the scope of the present effort". Body fluid compartments can be measured by dilution of a compound that distributes only in the space of interest. This thing was originally intended as an instrument to help scientists calculate dose following radiation exposure, and initially "it was agreed that the Task Group would limit its attention to those characteristics It is rarely referenced (because why would you), but if you dig around you will find that most of these textbooks get their information from the extensive and fascinating Report of the Task Group on Reference Man, by Snyder et al (1974). This material should seem very familiar it appears in the first chapters of almost every physiology textbook, often as a series of stacked bar graphs describing the body composition of the Ideal 70kg Person. Fluid compartments in the mammalian body broadly comprise two compartments, each with several subdivisions: intracellular fluid (ICF), which makes up approximately 60-65 of body water, and extracellular fluid (ECF), which makes up the other 35-40 of body water (for all practical purposes, the only solvent in the body is water ). communicates with the intracellular fluid, rather than the interstitial fluid.Transcellular fluid: ~1.5% (1050ml) fluid formed by the secretory activity of cells, Intracellular Fluid = 33% ( 23.1 litres) this volume is regulated by the movement of free water.Įxtracellular Fluid = 27% (18.9 litres) this volume is regulated by the movement of sodium. Note that this diagram places focus only on these three major fluid compartments. Plasma is the smallest fluid compartment (8 of total body water). Interstitial fluid contains 25 of the total body water. Higher in obesity, but as a lower proportion of body mass, as adipose tissue is only 10-20% water The intracellular fluid compartment contains most of the water in the body (67 of total).Total body water: 42 L (60% of total body mass)
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